Serie A Matchweek 5 brings several games that could already reshape the top of the table. Roma and Inter meet after perfect starts, Juventus host an inconsistent Atalanta side, while Fiorentina try to build on their recent improvement against Napoli.
We take a closer look at the three biggest fixtures, with two more worth watching.
888STARZ odds are correct at the time of writing and may change before kick-off.
Roma vs Inter — 12 points against 12
The biggest game of the round and the first serious test for the two strongest teams of the opening weeks.
Roma and Inter have both won their first four Serie A matches and head into Saturday with 12 points from 12.
Roma beat Torino 2-0 last time out, while Inter produced a remarkable comeback from 2-0 down to defeat Udinese 5-3.
Roma’s start has been built around balance. Gian Piero Gasperini’s side have given opponents very little while quickly finding effective combinations in attack.
Inter have shown something different: even when a match starts badly, they still have enough quality to turn it around.
888STARZ odds:
Roma — 2.80 | Draw — 3.52 | Inter — 2.67
There is almost nothing between them in the market. That makes sense: these are not just two major clubs, but two sides that have yet to drop a single point.
Juventus vs Atalanta — one side allows almost nothing, the other far too much
Juventus come into Sunday after their 5-0 Europa League win over NEC and now face an Atalanta side that has looked much less stable.
One stat tells the story particularly well: Juventus have allowed just 28 shots — the fewest in Serie A, while Atalanta have already faced 82 — the most in the league.
The Bergamo side have also lost their last two Serie A matches 2-1.
888STARZ odds:
Juventus — 1.77 | Draw — 3.96 | Atalanta — 5.04
The gap in the odds is already significant. It reflects more than home advantage — the two teams have simply started the season at very different levels.
Fiorentina vs Napoli — a new spark in Florence
Fiorentina’s start was poor enough for the club to make an early coaching change.
Paolo Vanoli’s return has already had an effect. Fiorentina have won two straight matches and scored seven goals across them.
Their league position is still difficult, though. After four rounds, Fiorentina have only three points, while Napoli have six.
That makes this game more interesting than the table alone suggests. The home side’s form is changing quickly.
888STARZ odds:
Fiorentina — 3.44 | Draw — 3.53 | Napoli — 2.27
Napoli remain favourites, but 2.27 away from home leaves plenty of room for Fiorentina to continue their recovery.
Two More Matches Worth Watching
Milan vs Lecce
Milan get a good opportunity to reset quickly after their disappointing European night against Benfica.
The market sees a huge gap:
888STARZ: 1.30 | 6.09 | 12.40
This is one of the clearest matchups of the European weekend. The main question is how quickly Milan can recover their rhythm after the midweek defeat.
Frosinone vs Como
This one is interesting less for the names and more for the table.
Como sit third after four rounds with 10 points and are already showing that last season’s progress was no accident.
888STARZ: 6.23 | 4.53 | 1.58
Even away from home, Cesc Fabregas’ side are priced as heavy favourites.
All Serie A Matchweek 5 Fixtures
| Match | Home | Draw | Away |
| Monza — Sassuolo | 2.89 | 3.46 | 2.63 |
| Bologna — Torino | 2.02 | 3.61 | 4.12 |
| Udinese — Cagliari | 2.31 | 3.36 | 3.52 |
| Roma — Inter | 2.80 | 3.52 | 2.67 |
| Venezia — Lazio | 3.89 | 3.73 | 2.04 |
| Fiorentina — Napoli | 3.44 | 3.53 | 2.27 |
| Frosinone — Como | 6.23 | 4.53 | 1.58 |
| Parma — Genoa | 3.23 | 3.15 | 2.57 |
| Juventus — Atalanta | 1.77 | 3.96 | 5.04 |
| Milan — Lecce | 1.30 | 6.09 | 12.40 |
The main question of the round is obvious: which team drops points first, Roma or Inter?
But there are other strong storylines around it. Juventus can complete an excellent week, Napoli travel to a Fiorentina side suddenly finding momentum, and Como are no longer entering games as a nice underdog story — they are doing so as a top-three team.
Those are the storylines worth revisiting once the round is over.